A Short-Step Synthetic Approach to Eudesmane Skeleton. A Synthesis of (±)-β-Eudesmol and Related Eudesmane Sesquiterpenes
نویسندگان
چکیده
منابع مشابه
Two eudesmane sesquiterpenes from Laggera pterodonta.
Two new eudesmane sesquiterpenes, 2alpha-hydroxy pterodontic acid (1) and pterodolide [3alpha-(2-methyl-2,3-epoxy)-butyric-4alpha-acetoxy-8beta-ethoxy eudesma-7(11)-en-8alpha,12-olide (2), along with five known compounds (3-7) were isolated from the aerial parts of Laggera pterodonta. Their structures were elucidated on the basis of spectroscopic methods. The immunosuppressive activity of the i...
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The eudesmane sesquiterpenes are an important class of natural products, with relevant biological activities. Although these compounds can be substituted at practically all the carbon atoms, there is current interest for examples substituted at both C-1 and C-6 (see Schemes 1 and 2). In this short report we present a new methodology for the concise synthesis of the 1,6-disubstituted eudesmane c...
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Transannular cyclizations of germacrone-4,5-epoxide under acidic and thermal conditions have been reported in our previous study. However, this process gave the different and interesting results under basic conditions. (4S,5S)-Germacrone-4,5-epoxide (1) was treated under basic conditions to yield four products (2-5). Compound 2 was an isomer of 1--(4S,5S,9Z)-4,5-epoxygermacra-7(11),9-dien-8-one...
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Species of the genus Verbesina (Asteraceae, tribe Heliantheae, subtribe Ecliptinae) have produced a range of eudesmane sesquiterpenes with cinnamate or a derived ester group, of which, αand β-verbesinolcoumarates were the first reported examples. Several species also afforded elemanolides, diterpenes, flavonoids, and biological active guanidines as Galegine, the toxic principle of V. enceloides...
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the frame semantic theory is a nascent approach in the area of translation studies which goes beyond the linguistic barriers and helps us to incorporate cognitive and cultural factors to the study of translation. based on rojos analytical model (2002b), which centered in the frames or knowledge structures activated in the text, the present research explores the various translation problems that...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1988
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.61.3770